15 nm Gold Nanospheres

Product Number

$50.00

  • Unagglomerated and monodisperse
  • Mean diameter: 15 nm ± 3 nm
  • Size distribution (CV) < 12%
  • NanoXact (0.05 mg/mL) and BioPure (1 mg/mL) concentrations, or dried
  • Citrate, tannic, PVP, lipoic acid, PEG, or BPEI surfaces
  • NanoXact citrate particles are in a 2 mM sodium citrate solution; others are in water

Product Lines

Tight Size
Distribution
Wide Variety
of Surfaces
Available
Dried
Guaranteed Sterile
& Endotoxin-Free
Highly
Concentrated
Lower
Cost
Learn more +
(certain products)

(certain products)
  • Monodisperse and unagglomerated
  • Standard colloidal concentration
  • Seven standard surfaces (citrate, tannic, PVP, lipoic acid, PEG, BPEI, silica)
  • Monodisperse and unagglomerated
  • Concentrated to 1 mg/mL
  • Extensively washed (10×)
  • Manufactured sterile
  • Low endotoxin levels
  • Six standard surfaces (citrate, tannic, PVP, lipoic acid, PEG, BPEI)

Which Surface Should I Choose?

Surface Displaceable Salt
Stability
Stable in
Water
Stable in
Alcohols
Stable in
Polar Organics
Stable in
Non-Polar Organics
Conjugatable Charge
at pH 7
Citrate Learn more +
  • Most commonly requested capping agent
  • Easily displaceable with other molecules for binding studies or custom functionalization
  • High degree of electrostatic stabilization
PVP (Polyvinylpyrrolidone) Learn more +
  • Associates very strongly to metal surfaces, giving excellent colloidal stability over a wide range of conditions
  • Nanoparticles can be dispersed in a wide variety of protic and aprotic polar solvents
  • Stable in high ionic strength solutions and at high concentrations
Lipoic Acid Learn more +
  • Dithiol forms a strong, stable bond with metal surfaces and the acid provides a highly negatively charged surface
  • The free carboxylic acid can be used for conjugation or labeling; contact us to discuss your application
BPEI (Branched Polyethyleneimine) Learn more +
  • Highly aminated, positively charged organic surface coating
  • Large number of free amines for conjugation to targeting molecules
PEG (Polyethylene Glycol) Learn more +
  • Provides excellent dispersibility in water and protic solvents and increases compatibility in biological systems
  • Covalently bound to the nanoparticle surface to prevent desorption over time and increase colloidal stability
  • Custom variants available with PEG of different molecular weights and free functional groups for labeling or conjugation

Certificate of Analysis Examples

Please note that these are representative Certificates of Analyses (CoAs) provided as examples for this product. We provide a unique batch-specific CoA with each product during shipment; only the CoA that arrives with your product should be referred to for actual characterization and measurement data. If you would like an electronic copy of the CoA for the product you received or the material(s) we currently have in stock, please contact us.

Product Line Surface Example Certificate of Analysis Product # Price
N NanoXact, 0.05 mg/mL Citrate Download ↓ AUCN15-25M $50+
N NanoXact, 0.05 mg/mL Citrate Download ↓ AUCN15-100M $165+
N NanoXact, 0.05 mg/mL Citrate Download ↓ AUCN15-500M $575+
N NanoXact, 0.05 mg/mL Citrate Download ↓ AUCN15-1000M $895+
N NanoXact, 0.05 mg/mL Tannic Acid Download ↓ AUTN15-25M $57+
N NanoXact, 0.05 mg/mL Tannic Acid Download ↓ AUTN15-100M $185+
N NanoXact, 0.05 mg/mL Tannic Acid Download ↓ AUTN15-500M $650+
N NanoXact, 0.05 mg/mL Tannic Acid Download ↓ AUTN15-1000M $1,025+
N NanoXact, 0.05 mg/mL PVP Download ↓ AUPN15-25M $57+
N NanoXact, 0.05 mg/mL PVP Download ↓ AUPN15-100M $185+
N NanoXact, 0.05 mg/mL PVP Download ↓ AUPN15-500M $650+
N NanoXact, 0.05 mg/mL PVP Download ↓ AUPN15-1000M $1,025+
N NanoXact, 0.05 mg/mL PEG Download ↓ AUGN15-25M $57+
N NanoXact, 0.05 mg/mL PEG Download ↓ AUGN15-100M $185+
N NanoXact, 0.05 mg/mL PEG Download ↓ AUGN15-500M $650+
N NanoXact, 0.05 mg/mL PEG Download ↓ AUGN15-1000M $1,025+
N NanoXact, 0.05 mg/mL Lipoic Acid Download ↓ AULN15-25M $57+
N NanoXact, 0.05 mg/mL Lipoic Acid Download ↓ AULN15-100M $185+
N NanoXact, 0.05 mg/mL Lipoic Acid Download ↓ AULN15-500M $650+
N NanoXact, 0.05 mg/mL Lipoic Acid Download ↓ AULN15-1000M $1,025+
N NanoXact, 0.05 mg/mL BPEI Download ↓ AUBN15-25M $65+
N NanoXact, 0.05 mg/mL BPEI Download ↓ AUBN15-100M $215+
N NanoXact, 0.05 mg/mL BPEI Download ↓ AUBN15-500M $750+
N NanoXact, 0.05 mg/mL BPEI Download ↓ AUBN15-1000M $1,150+
D NanoXact, Dried PVP Download ↓ AUPD15-1MG $225+
D NanoXact, Dried PVP Download ↓ AUPD15-5MG $950+
D NanoXact, Dried PVP Download ↓ AUPD15-10MG $1,625+
D NanoXact, Dried PVP AUPD15-30MG $3,450+
B BioPure, 1 mg/mL Citrate Download ↓ AUCB15-1M $195+
B BioPure, 1 mg/mL Citrate Download ↓ AUCB15-5M $815+
B BioPure, 1 mg/mL Citrate Download ↓ AUCB15-10M $1,395+
B BioPure, 1 mg/mL Citrate AUCB15-30M $2,995+
B BioPure, 1 mg/mL Tannic Acid Download ↓ AUTB15-1M $225+
B BioPure, 1 mg/mL Tannic Acid Download ↓ AUTB15-5M $950+
B BioPure, 1 mg/mL Tannic Acid Download ↓ AUTB15-10M $1,625+
B BioPure, 1 mg/mL Tannic Acid AUTB15-30M $3,450+
B BioPure, 1 mg/mL PVP Download ↓ AUPB15-1M $225+
B BioPure, 1 mg/mL PVP Download ↓ AUPB15-5M $950+
B BioPure, 1 mg/mL PVP Download ↓ AUPB15-10M $1,625+
B BioPure, 1 mg/mL PVP AUPB15-30M $3,450+
B BioPure, 1 mg/mL PEG Download ↓ AUGB15-1M $225+
B BioPure, 1 mg/mL PEG Download ↓ AUGB15-5M $950+
B BioPure, 1 mg/mL PEG Download ↓ AUGB15-10M $1,625+
B BioPure, 1 mg/mL PEG AUGB15-30M $3,450+
B BioPure, 1 mg/mL Lipoic Acid Download ↓ AULB15-1M $225+
B BioPure, 1 mg/mL Lipoic Acid Download ↓ AULB15-5M $950+
B BioPure, 1 mg/mL Lipoic Acid Download ↓ AULB15-10M $1,625+
B BioPure, 1 mg/mL Lipoic Acid AULB15-30M $3,450+
B BioPure, 1 mg/mL BPEI Download ↓ AUBB15-1M $250+
B BioPure, 1 mg/mL BPEI Download ↓ AUBB15-5M $1,050+
B BioPure, 1 mg/mL BPEI Download ↓ AUBB15-10M $1,795+
B BioPure, 1 mg/mL BPEI AUBB15-30M $3,850+

Need help reading our Certificates of Analysis? +

Gold Nanoparticle Applications

Diagnostic Applications

Gold nanopaticles are readily conjugated to antibodies and other proteins due to the affinity of sulfhydyl (-SH) groups for the gold surface, and gold-biomolecule conjugates have been widely incorporated into diagnostic applications, where their bright red color is used in home and point-of-care tests such as lateral flow assays.  

Biomedical Applications

Gold nanomaterials can be conjugated to biomolecules to specifically target cancer cells, and used for photothermal cancer therapy, where their tunable optical properties cause them to convert laser light into heat and selectively kill cancerous cells.   

Plasmonics

Gold nanoparticles have unique optical properties because they support surface plasmons. At specific wavelengths of light the surface plasmons are driven into resonance and strongly absorb or scatter incident light. This effect is so strong that it allows for individual nanoparticles as small as 30 nm in diameter to be imaged using a conventional dark field microscope.  This strong coupling of metal nanostructures with light is the basis for the new field of plasmonics.  Applications of plasmonic gold nanoparticles include biomedical labels, sensors, and detectors. The gold plasmon resonance is also the basis for enhanced spectroscopy techniques such as Surface Enhanced Raman Spectroscopy (SERS) and Surface Enhanced Fluoressence Spectroscopy which can be used to detect analytes with ultrahigh sensitivity. 

Ultra Uniform Gold Nanospheres

Our standard Au nanospheres have a variety of useful surface chemistries and narrow size distributions (CV < 15%), appropriate for a variety of applications ranging from lateral flow assays to optical coatings. Some applications, however, such as multiplexed dark field labeling or standards for nanoparticle size and shape, require even tighter tolerances on shape and size dispersity. For these applications, nanoComposix has successfully manufactured ultra-uniform, monodisperse gold nanospheres with sizes tunable from 10 nm up to 200 nm. As shown below, these gold nanoparticles have a nearly perfect spherical shape, smooth surfaces, and impressively narrow size distributions (CV < 6%, and for many sizes CV < 4%).

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Optical and Scattering Properties

Due to their high uniformity in size and shape, these Au nanospheres scatter a single color of light under dark field microscope imaging (shown below). The high purity of their light scattering signatures makes these nanospheres perfect scattering labels for imaging and building blocks for plasmonic nanostructures and devices.

Surface Chemistry

The gold nanospheres are stabilized with citrate in an aqueous solution. With their stable, easily displaceable surface chemistry, the gold nanospheres can be readily functionalized with a wide variety of molecules, including polymers and small molecules with desired functional groups, inorganic coatings such as silica, and biomolecules including DNA and antibodies for your application.

Contact us to learn more