nanoComposix products are used as international standards for determining environmental and health effects of nanoparticles.
Learn more about nanotoxicology +
Nanotoxicology is the study of the toxicity of nanomaterials and focuses on how the size and unique properties of nanoparticles influences their impact on human health and the environment. Nanosafety is a field that aims to understand the physical and chemical characteristics that can be engineered into a particle in order to maximize its safety. Together these two disciplines provide fundamental research results to support the rapidly increasing use of engineered nanoparticles in ways that are safe and sustainable.
To understand the structure-activity relationship of nanoparticles interacting with biological systems, it is important to conduct studies with precisely engineered nanomaterials that are highly characterized. By performing a set of experiments where only a single characteristic of the nanoparticle is altered, trends associated with that characteristic can be determined. Understanding the effect of each parameter allows for generalizations to be made for the more complex and relevant nanoparticles that are being produced and utilized at industrial scales. Learn more ❯
NanoComposix has been supporting the nanotoxicology community for over 10 years and our particles have been included in hundreds of scientific publications on nanotoxicology and nanosafety. We have the largest library in the world of silver and gold nanoparticle variants, allowing for different combinations of material, size, shape, and surface chemistry to be utilized to test hypotheses. Our BioPure branded particles are extensively washed to remove residual reagents, provided at higher particle concentrations, are sterile filtered, and have low endotoxin levels. Each lot is extensively characterized to give researchers the clearest understanding of the material properties being tested.
Product Line | Description | Available Materials | Available Surfaces | CV | Concentration | Available Dried | Buy | nanoComposix University |
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Guaranteed low endotoxin | Gold, silver, platinum, magnetite | Multiple | < 18% | 1 mg/mL | No | See products | Learn more | |
For bioconjugation (lateral flow assays, etc.) | Gold | Multiple | < 15% | Varies; usually 20 OD | Yes | See products | Learn more | |
Widest combination of materials and surfaces | Gold, silver, silica, platinum, magnetite | Multiple | Varies; usually < 15% | Varies | Yes | See products | Learn more | |
Most monodisperse | Gold | PEG-carboxyl | < 5% | 0.05 mg/mL | No | See products | Learn more | |
Do none of these work for you? Request a Custom Nanomaterial | ||||||||
We also offer a variety of nanoparticle characterization services |
Surface | Charge | Characteristics | Available Materials | Buy | NCX University |
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Bare (Citrate) | Easiest standard surface to displace with other molecules. | Gold, silver, platinum | See products | Learn more | |
Aminated (BPEI) | Covalently bound. Conjugatable surface. | Gold, silver | See products | Learn more | |
Carbonate | For biocojugation. Smaller, less complex molecule with a lower affinity to gold nanoparticle surface than citrate. | Gold | See products | Learn more | |
Carboxyl/Lipoic Acid | Covalently bound. Conjugatable surface. | Gold, silver | See products | Learn more | |
Dodecanethiol | Redispersible and stable in non-polar organic solvents. | Gold, silver | See products | Learn more | |
NHS | For quick and easy bioconjugation – no EDC/NHS activation required. | Gold | See products | ||
PEG | Highest stability in aqueous buffers and polar organic solvents. | Gold, silver | See products | Learn more | |
Polystyrene | Hydrophobic surface that allows for dispersion in a wide range of polar organic solvents. | Gold | See products | Learn more | |
PVP | Large polymer surface. Stable in a wide variety of solvents. | Gold, silver, magnetite | See products | Learn more | |
Silica Shell | Greatest solvent compatibility. Preserves plasmonic properties upon deposition. | Gold, silver, silica | See products | Learn more | |
Silica Shell (Aminated) | Conjugatable surface. Greatest solvent compatibility. Preserves plasmonic properties upon deposition. | Gold, silver, silica | See products | Learn more | |
Streptavidin | For convenient bioconjugation of any biotinylated antibody, protein, or oligonucleotide. | Gold | See products | ||
Tannic Acid | Less easily displaced than citrate but stable in more buffers. | Gold | See products | Learn more | |
Do none of these work for you? Request a Custom Surface |
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