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4 nm Dodecanethiol-Stabilized Silver Nanospheres

Product Number


  • Unagglomerated and monodisperse
  • Dodecanethiol functionalized surface
  • Mean diameter: 4.0 nm ± 1.0 nm
  • Size distribution (CV) < 25%
  • Available dried and can be reconstituted in your solvent of choice

Product Lines

Tight Size
Wide Variety
of Surfaces
Guaranteed Sterile
& Endotoxin-Free
Learn more +
(certain products)

(certain products)
  • Monodisperse and unagglomerated
  • Standard colloidal concentration
  • Seven standard surfaces (citrate, tannic, PVP, lipoic acid, PEG, BPEI, silica)

Which Surface Should I Choose?

Surface Displaceable Salt
Stable in
Stable in
Stable in
Polar Organics
Stable in
Non-Polar Organics
Conjugatable Charge
at pH 7
Dodecanethiol Learn more + N/A
  • Hydrophobic coating renders particles soluble in organic solvents and compatible with non-polar polymer composite materials
  • Can be dispersed in low surface-energy solvents for coating applications requiring uniform particle deposition

Certificate of Analysis Examples

Please note that these are representative Certificates of Analyses (CoAs) provided as examples for this product. We provide a unique batch-specific CoA with each product during shipment; only the CoA that arrives with your product should be referred to for actual characterization and measurement data. If you would like an electronic copy of the CoA for the product you received or the material(s) we currently have in stock, please contact us.

Product Line Surface Example Certificate of Analysis Product # Price
D NanoXact, Dried Dodecanethiol Download ↓ AGDD4-1MG $120+
D NanoXact, Dried Dodecanethiol Download ↓ AGDD4-5MG $475+
D NanoXact, Dried Dodecanethiol Download ↓ AGDD4-25MG $1,375+
D NanoXact, Dried Dodecanethiol Download ↓ AGDD4-50MG $2,150+

Need help reading our Certificates of Analysis? +

Silver Nanoparticle Applications

Silver nanoparticles are one of the most commonly utilized nanomaterials due to their anti-microbial properties, high electrical conductivity, and optical properties.

Medical Applications

Silver nanopaticles are widely incorporated into wound dressings, and are used as an antiseptic and disinfectant in medical applications and in consumer goods. Silver nanoparticles have a high surface area per unit mass and release a continuous level of silver ions into their environment. The silver ions are bioactive and have broad spectrum antimicrobial properties against a wide range of bacteria. By controlling the size, shape, surface and agglomeration state of the nanoparticles, specific silver ion release profiles can be developed for a given application.

Conductive Composites

Incorporation of silver particles into plastics, composites, and adhesives increases the electrical conductivity of the material. Silver pastes and epoxies are widely utilized in the electronics industries. Silver nanoparticle based inks are used to print flexible electronics and have the advantage that the melting point of the small silver nanoparticles in the ink is reduced by hundreds of degrees compared to bulk silver. When scintered, these silver nanoparticle based inks have excellent conductivity.


Silver nanoparticles have unique optical properties because they support surface plasmons. At specific wavelengths of light the surface plasmons are driven into resonance and strongly absorb or scatter incident light. This effect is so strong that it allows for individual nanoparticles as small as 20 nm in diameter to be imaged using a conventional dark field microscope. This strong coupling of metal nanostructures with light is the basis for the new field of plasmonics. Applications of plasmonic silver nanoparticles include biomedical labels, sensors, and detectors. It is also the basis for analysis techniques such as Surface Enhanced Raman Spectroscopy (SERS) and Surface Enhanced Fluorescent Spectroscopy.


There is increasing interest in utilizing the large scattering and absorption cross sections of plasmonic silver nanoparticles for solar applications. Since the nanoparticles act as efficient optical antennas, very high efficiencies can be obtained when the nanoparticles are incorporated into collectors.

Custom Silver Nanomaterials

NanoComposix has extensive experience with the synthesis and development of complex silver nanomaterials and has produced a broad assortment of well-characterized, precisely-tuned silver nanoparticles on a custom basis for many customers. We are able to synthesize silver nanomaterials of varying sizes and shapes, surface functionalities, and compatibility with different solvents and composite materials.

Contact us today to inquire about your own custom silver nanoparticle needs.

Spherical Silver Nanoparticles

Size: In addition to the wide range of standard sizes of silver nanospheres that we have in stock, we have fabricated additional sizes of uniform, unagglomerated particles on demand for customers. NanoComposix has successfully manufactured sizes spherical silver nanoparticles for customers ranging from 300 nm up to 2 μm, as shown below.

300 nm silver 600 nm silver 2 µm silver

Surface Chemistry & Coatings: Our standard silver nanoparticles have a variety of different anionic and cationic capping ligands available, ranging from displaceable small molecules to polymer coatings. In addition, we can fabricate nanomaterials with specific functional groups, polymers, biomolecules, and inorganic coatings. Examples of custom aqueous solvent compatible surfaces that we have fabricated include polyvinyl alcohol (PVA), polyethylene glycol (PEG) of different molecular weights and different terminal functional groups, or biomolecules such as streptavidin. We have coated particles with inorganic coatings like titania (TiO2) and applied our uniform and precisely controlled silica coatings to a wide range of sizes beyond our standard products. We have also successfully fabricated hydrophobic organic solvent compatible surfaces such as alkylsilane-, phenyl- and cyclic azasilane-functionalized silica groups.

150 nm silica shelled silver 40 nm streptavidin silver 70 nm titania shelled silver

Solvent Selection

To redisperse the particles, we recommend adding an appropriate solvent from the Table below to the dried powder and vortexing for 30 seconds. After redispersion, samples should be stored at 4°C and away from light, as described in our Storage and Handling instructions.

Solvent Refractive Index, nNanopowder Solubility
Toluene 1.50 High
Chloroform 1.45 High
Dichloromethane 1.42 High
Hexane 1.38 High
THF 1.41 High
DMF 1.43 None
DMSO 1.48 None
Acetonitrile 1.34 None
Isopropanol 1.38 None
Ethanol 1.36 None
Methanol 1.33 None
Water 1.34 None

Effect of Solvent on Nanoparticle Optical Properties

UV-visible spectroscopy can be used to detect the presence of aggregation or changes in particle size; such effects are readily observed in the absorption spectrum as a change in the width of the plasmon peak and/or the appearance of a secondary peak that is red-shifted from the plasmon peak. Samples of a hexane dispersion of 4 nm-diameter dodecanethiol-coated Ag nanoparticles were dried and re-suspended in a variety of organic solvents. The absorption spectrum of the resuspended sample is compared with that of the original hexane dispersion in the figures below.

Comparison of the UV-visible spectrum of a dispersion of 4 nm dodecanethiol-coated Ag nanoparticles in hexane that have been dried and re-suspended in different organic solvents.

Small changes in the UV-visible absorption spectra of the redispersed samples are seen when compared with the original hexane dispersion. The shifting and broadening of the the spectra are typical of those seen during solvent transfer due to a change in the refractive index of the solvent, and are not due to changes in particle size or agglomeration.