Tailored Feasibility for Your Next Milestone
Custom Mesoporous Silica Nanoparticle Development
Advance your formulation with mesoporous silica nanoparticles optimized for your API and performance goals. Start with an established platform or explore custom particle development to meet your application's requirements.
Schedule a ConsultationMesoporous Silica Carriers Adjusted for Your Application
Begin with a screening of API compatibility, loading capacity, or your desired particle specifications.
API Loading & Formulation Feasibility
Evaluate MSN compatibility with your API through particle screening and loading studied. Assess initial loading capacity and suspension behavior of the API-carrier system.
Custom Mesoporous Silica Nanoparticle Engineering
Explore particle structure and surface chemistry strategies tailored to your application. Identify and refine key particle attributes to support your performance requirements.
Tailor Mesoporous Silica Properties to Your Application
Optimize particle properties and formulation performance around your development objectives.
API Loading & Release
Assess API compatibility and optimize loading, retention, and release.
Particle & Pore Engineering
Optimize particle size, morphology, pore structure, and surface area.
Surface Functionalization
Customize internal and external surface chemistry to support loading, conjugation, and targeting.
Delivery System Stability
Assess aggregation, dispersion stability, and payload retention during storage and processing.
Analytical Characterization
Characterize particle morphology, pore properties, surface chemistry, and API loading.
Process Development & Scale-Up
Optimize synthesis, purification, and processing for reproducible manufacturing and scale-up.
Accelerate Your Development with Focused Feasibility Studies
 Mesoporous Silica NanoFab Packages |
 NanoFab QuickStart |
Best Value NanoFab Pro |
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| Best Fit | Initial feasibility or candidate screening |  |
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| Formulation or particle optimization |  |
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| Scope | MSN platform & pore structure screening | |
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| API compatibility & loading feasibility | |
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| Surface functionalization | |
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| Custom particle & pore optimization | |
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| Loading, release & stability optimization | |
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| Analytical method development | |
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| Process optimization & scale-up assessment | |
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| Pricing | Starting at | $15,000 | $40,000 |
Representative development activities are shown. Each NanoFab project is scoped around your specific technical objectives, with agreed-upon activities, deliverables, and pricing.
Data to Inform Development Decisions
Generate technical data to assess feasibility, compare candidate formulations, and guide your next development decision.
Advance Your Formulation Beyond Feasibility
As your mesoporous silica development program progresses, build on initial feasibility findings with further formulation optimization, process development, and scale-up.
Access expanded process development and manufacturing support through our integrated Nanomedicine CDMO Services, with project scope and quality requirements aligned with your next development milestone.
Explore MSN Solutions for Your Therapeutic Application
Customizable pore structures and surface chemistries enable mesoporous silica platforms to address a range of therapeutic formulation challenges.
Small Molecule Drug Delivery
Explore MSN formulations for small molecule API loading, retention, and targeted delivery.
Nucleic Acid & Biologic Delivery
Evaluate larger pore structures and surface chemistries for loading nucleic acids, proteins, and other biomolecular payloads.
Multifunctional Therapeutic Platforms
Develop custom MSN structures to incorporate targeting ligands, functional surfaces, or imaging components.
MSN Formulation Strategies in Practice
Mesoporous silica development strategies performed at nanoComposix have supported different therapeutic challenges throughout the years.
Rapid Platform Screening
Screened MSN platforms and pore-capping strategies to optimize API loading, release, and stability. Rapid feasibility support enabled a biopharmaceutical developer to select a formulation for preclinical development.
R&D Through Scale-Up
A customer initially adopted nanoComposix MSNs for early-stage research. As their program advanced, we scaled production toward manufacturing-level volumes to support continued development.
Technology Transfer
Transferred and optimized a mesoporous silica microrod synthesis process for a CAR-T therapy research program. These materials supported the development of specialized materials for T-cell engineering.
Complex Biomolecule Delivery
Engineered MSNs for targeted mRNA delivery in HIV vaccine research. The approach induced HIV-specific immune responses, demonstrating the potential of MSNs for complex biomolecule delivery.
Accelerate Feasibility with Established MSN Platforms
Start with an existing mesoporous silica platform or develop a fully custom particle tailored to your application. Established MSN structures can provide a practical starting point for evaluating API compatibility, loading behavior, and surface modifications.
Need help choosing a starting material? See the Mesoporous Silica Selection Guide.
Advance Your Mesoporous Silica Development Program
Whether you're evaluating API-loading feasibility, or addressing a challenge with your existing formulation, start with the technical questions that matter most to your program.
Discuss your target specifications, available data, and next development milestone. Together, we can define a focused feasibility project with clear objectives and a path for continued development.
FAQs: Custom Mesoporous Silica Development
Can you evaluate API-loading feasibility before we've selected an MSN platform?
Yes. We can start with the catalog variants most suitable for your API and application, then further customize as needed.
Can you modify an existing MSN formulation to improve performance?
Yes. We can optimize particle size, pore structure, surface chemistry, and/or processing conditions to improve API loading, release, stability, and reproducibility.
What information helps define a MSN feasibility study?
Helpful information includes your API properties, target loading and release performance, and any formulation requirements. Preliminary data is useful but not required.
What analytical characterization and deliverables can be included?
Characterization methods will be selected based on your application's requirements and may include:
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Particle Characterization: Size, morphology, pore structure, and surface chemistry (TEM, DLS, BET, zeta potential, FTIR).
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Formulation Performance: API loading, recovery, release, and stability (HPLC, UV-Vis, fluorescence).
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Deliverables: A technical report summarizing results, key findings, and recommended next steps.
Can you work from a customer-developed MSN synthesis or loading process?
Yes. We can build on your existing protocols to optimize processing, improve reproducibility, support scale-up, or facilitate technology transfer. Development activities are tailored to your process and project goals.