Dodecanethiol is a hydrophobic molecule that provides particles with solubility in organic solvents and compatibility with non-polar polymer composite materials as well as promoting dispersion in low surface-energy solvents for coating applications requiring uniform particle deposition. The thiol group provides a very strong bond to the gold particle surface, leaving the hydrophobic alkyl chain exposed to solution. The dodecane thiol gives steric stability by providing a physical barrier that prevents particle aggregation in the dried state and allows particles to be dried and re-suspended in organic solvents without particle agglomeration.
Dodecanethiol is only available for sub-10 nm sizes of gold and silver; for larger sizes requiring organic compatibility, we recommend polystyrene.
- Disperses in organic solvents
- Can be dried (solvent evaporated at ambient pressure or vacuum assisted) and re-dispersed in organic solvents without agglomeration
Representative Source: 1-dodecanethiol (Sigma Aldrich, 471364)
Molecular Weight: 202.40
Displaceable: Not displaceable – strong binding affinity to the particle surface vial the thiol group
- Soluble in non-polar solvents
- Incorporation of particles in non-polar solvents and materials
- Biodiagnostic and nanomedicine applications
- Photothermal applications
In-vitro and in-vivo toxicology experiments