nanoComposix is now a Fortis Life Sciences Company. Learn more + Email Newsletter Signup

Performance Comparison of Commonly Used Nanoparticle Probes in SARS-CoV-2 Nucleocapsid Protein LFA

Lateral flow assays are simple diagnostic devices that can detect a variety of biomarkers in saliva, nasal fluid, urine, and other sample types. The control and test bands on a standard lateral flow test are generated using strongly colored reporter probes, often nanoparticles, bound to a white nitrocellulose strip.

In this white paper, we compared the sensitivity of nanoComposix’s blue-green 150 nm Gold Nanoshells with 40 nm Carboxyl Gold Nanospheres (CGN), Europium latex, and colored latex probes. We conjugated the probes to an anti-SARS-CoV-2 nucleocapsid antibody and incorporated them into a lateral flow sandwich assay. Our results show that both Gold Nanoshells and colored latex had the highest level of sensitivity.

To download white paper please fill out this form:

* = required