Colloidal Gold Nanoparticle Characterization Service
The nanoComposix Colloidal Gold Nanoparticle Characterization Service provides side-by-side DLS and UV-Vis characterization of your colloidal gold nanoparticle or conjugate against a nanoComposix BioReady reference material. Designed for diagnostic assay developers and IVD manufacturers, the service can help identify particle-level differences when evaluating alternative suppliers, investigating lot variability, or troubleshooting assay performance.
Services start at $500.
Included Analyses
- Dynamic Light Scattering (DLS): hydrodynamic diameter, size distribution, and polydispersity
- UV-Visible Spectroscopy (UV-Vis): plasmon peak position, peak width, and spectral characteristics
- Reference comparison: side-by-side comparison with the closest applicable nanoComposix BioReady gold nanoparticle or conjugate
- Technical interpretation: assessment of particle size, spectral behavior, colloidal stability, and evidence of aggregation
Technical Resources
- Dynamic Light Scattering (DLS) Measurement and Analysis Guide
- UV-Vis Spectroscopy Measurement and Analysis Guide
How It Works
- Fill out the sample submission form or contact us to get started.
- We review your sample and select the most appropriate BioReady reference for comparison.
- Once your order is accepted, send us your sample.
- nanoComposix performs DLS and UV-Vis analysis on your material and the selected reference.
- You receive a written report with comparative data and technical interpretation within 10 business days.
When to Use This Service
- Evaluate an alternative colloidal gold supplier
- Investigate changes in assay signal or conjugation performance
- Compare nanoparticle lots or identify potential sources of variability
- Support component qualification or change-assessment activities
- Establish comparative particle data during assay development
Frequently Asked Questions
Who should use colloidal gold nanoparticle characterization?
Diagnostic assay developers and IVD manufacturers evaluating colloidal gold materials or investigating whether particle properties may be contributing to assay variability, inconsistent signal, aggregation, or conjugation issues.
What can colloidal gold nanoparticle characterization identify?
DLS and UV-Vis can identify differences in hydrodynamic size, size distribution, spectral properties, and evidence of aggregation or colloidal instability. These measurements can help determine whether a nanoparticle material differs meaningfully from the selected BioReady reference.
How much sample is required?
Typical sample requirements are 0.5–1.0 mL, depending on particle concentration. Final sample requirements are confirmed during service intake.
What is included in the characterization report?
The report includes DLS and UV-Vis data for your sample, comparison with the selected BioReady reference material, and a summary interpretation of the key findings.
How long does characterization take?
Reports are typically delivered within 10 business days after the sample is received and the order is accepted.
Can this service help with supplier or lot changes?
Yes. Comparative characterization can help determine whether an alternative supplier, new lot, or changed material differs in measurable particle properties from a known reference. The resulting data can support technical investigations, component qualification, and risk-based change assessments.
Does this service determine whether two materials will perform the same in my assay?
No. DLS and UV-Vis characterize important particle properties, but equivalent characterization results do not guarantee equivalent assay performance. Functional testing in the intended assay remains important.